Endocrine Abstracts

The conducted national screening of Bulgarian pregnant women showed a frequency of Hyperglycemia among them of 14.4%. It is known that a number of factors have a significant impact on this disorder. The aim: to assess risk factors for the development of Hyperglycemia in pregnant women in Bulgaria.Material: We screened 547 pregnant women, mean age 30.49±5.12 years, divided into two groups: up to 24 gestational week –g.w. (n-386, 70.6%) and after 2...

In 2005, the evaluation of an international expert group* placed Bulgaria among those who successfully overcame the problem of ‘iodine deficiency’. The aim of the study is to assess the current iodine status in pregnant women in two main regions of Bulgaria - with a known iodine deficiency and other with sufficiency in the past.Material: A cross-sectional multicenter population-based study was conducted in a total of 84 settlements from the two...

Bulgaria is also among the countries with national data on the prevalence of Diabetes published in the Diabetes Atlas of the International Diabetes Federation’2019, but did not provide data on the incidence of Hyperglycemia in pregnant Bulgarian women.Purpose: The Bulgarian Society of Endocrinology organized and conducted screening for Hyperglycemia in pregnant women in 2019.Material and Methods: 547 pregnant women from 10 re...

In Bulgaria there are epidemiological data for the population of 20–80 years for the frequency of thyroid dysfunction – 6.3% hypothyroidism and 3.7% hyperthyroidism (Bulgarian Society of Endocrinology, 2012). So far, there is no national data on the incidence of thyroid disorders in pregnant women, which is a major lack of the health care system and the purpose of this study is to fill this gap.Material and Methods: We studied 547 pregnant Bu...

The nodular goiter is the most prevalent thyroid disorder. Its prevalence increases with age and reaches over 70%. The aim of the study was to compare the nodule prevalence in two population-based studies, carried in Bulgaria in 2006 and 2012.Material and methods: Two thousand four hundred and two subjects (1347 female and 1053 male, age range 20–94 years) were included in 2006 and 2022 (1073 female and 949 male, 20–88 years) in 2012. All subje...

Metabolic abnormalities in adult GH deficiency (AGHD) determine its significance as a disease associated with increased cardiovascular risk. However, recent contradictory data about the long-term beneficial effects of GH replacement, especially on cardiovascular risk, provoked some further analysis of its contributory factors.Aim of the study: To identify the individual risk factors of metabolic syndrome (MS) in AGHD and to compare the prevalence and the...

The aim of the study was to investigate the relationship among the indices of insulin resistance (IR), the lipid parameters and thyroid function in euthyroid adults.Material and methods: Two hundred and sixteen euthyroid adults, mean age 57.08±13.81 years (112 female and 104 male) were included. Serum lipirds, Immunoreactive insulin, glucose, TSH, waist circumference (WC), body height and weight were measured. HOMAi and BMI were calculated.<p cl...

Background: Experimental studies have demonstrated that prolactin is a potent immunomodulator influencing both humoral and cell-mediated responses. In accordance with these data, our retrospective studies revealed higher prevalence of autoimmune thyroid diseases in prolactinoma patients compared to general population.Design: A prospective cross-sectional case–control study was carried out in a single tertiary referral centre.A...